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Author Boucher, R.; Knefati, S.; Ouimet, C.-A. url  doi
openurl 
  Title (up) Conservation du ciel nocturne : surveillance de l’éclairage extérieur et de la pollution lumineuse au parc national et à la Réserve internationale de ciel étoilé du Mont-Mégantic Type Journal Article
  Year 2018 Publication Le Naturaliste canadien Abbreviated Journal Le Naturaliste canadien  
  Volume 142 Issue 3 Pages 88  
  Keywords Skyglow  
  Abstract English:

Although seemingly unchanging, today, our ability to see stars on a dark night is in danger of disappearing. The reason for this is the widespread growth of light pollution from inadequate lighting systems. This study, which used a range of methods, presents the results of light pollution measurements taken within the Mont-Mégantic International Dark Sky Reserve (MMIDSR), which was created in 2007 to protect the quality of astronomical observations and research at the Mont-Mégantic Observatory, and to preserve the exceptional starry nightscape visible from the site. Two essential elements of artificial night lighting were considered: its source and its diffusion in the atmosphere. Analyses showed that despite a global trend towards an increase in light levels, population growth on the outskirts of the Parc national du Mont-Mégantic, and the arrival of problematic types of lighting fixtures on the market, the level of light pollution in the MMIDSR has remained stable over the last 10 years, not only at the zenith but across the entire sky.

French:

Pourtant d’apparence immuable, le ciel étoilé est aujourd’hui menacé de disparition. La cause est la croissance généralisée de la pollution lumineuse, résultat de l’utilisation de dispositifs d’éclairage inadéquats. Nous présentons ici les résultats de la mesure de cette pollution obtenue par différentes approches méthodologiques sur le territoire de la Réserve internationale de ciel étoilé du Mont-Mégantic (RICEMM). La RICEMM a été créée en 2007 afin de protéger la qualité des observations astronomiques et de recherche de l’observatoire du mont Mégantic, ainsi que pour conserver les paysages étoilés exceptionnels du site. Deux aspects incontournables de la lumière artificielle nocturne ont été pris en compte : ses sources, ainsi que sa diffusion dans l’atmosphère. Les analyses démontrent que le niveau de pollution lumineuse est resté stable depuis 10 ans dans la RICEMM, tant au zénith que pour l’ensemble du ciel, et ce, malgré une tendance mondiale à la hausse des niveaux d’éclairement, l’augmentation de la population dans la périphérie du parc national du Mont-Mégantic et l’arrivée sur le marché de types de luminaires problématiques.
 
  Address  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language French Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0028-0798 ISBN Medium  
  Area Expedition Conference  
  Notes Approved no  
  Call Number GFZ @ kyba @ Serial 2004  
Permanent link to this record
 

 
Author Matveyenko, A.V. url  doi
openurl 
  Title (up) Consideration for Circadian Physiology in Rodent Research Type Journal Article
  Year 2018 Publication Physiology (Bethesda, Md.) Abbreviated Journal Physiology (Bethesda)  
  Volume 33 Issue 4 Pages 250-251  
  Keywords Animals; Commentary  
  Abstract  
  Address Mayo Clinic , Rochester, Minnesota  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1548-9221 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:29873599 Approved no  
  Call Number GFZ @ kyba @ Serial 1935  
Permanent link to this record
 

 
Author Maroni, M.J.; Capri, K.M.; Cushman, A.V.; Monteiro De Pina, I.K.; Chasse, M.H.; Seggio, J.A. url  doi
openurl 
  Title (up) Constant light alters serum hormone levels related to thyroid function in male CD-1 mice Type Journal Article
  Year 2018 Publication Chronobiology International Abbreviated Journal Chronobiol Int  
  Volume 35 Issue 10 Pages 1456-1463  
  Keywords Animals  
  Abstract Disruptions to the circadian rhythm can lead to altered metabolism. Modification of thyroid function may be a reason why circadian misalignment may contribute to future metabolic disorders. We investigated whether circadian disruption through constant light (LL) can lead to variations in hormone levels associated with thyroid function. Mice were exposed to LL or a 12:12 Light:Dark (LD) cycle for 6 weeks; then glucose tolerance and thyroid hormone levels were measured at ZT 6 and ZT 18. There was day/night variation in glucose tolerance, but LL had no effect. LL reduced TSH, increased fT4, and abolished day/night variation in fT3 and leptin. These findings illustrate that LL alters thyroid-related hormones, providing evidence of a link between circadian disruption and thyroid function.  
  Address a Department of Biological Sciences , Bridgewater State University , Bridgewater , MA , USA  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0742-0528 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:29953263 Approved no  
  Call Number GFZ @ kyba @ Serial 1958  
Permanent link to this record
 

 
Author Madahi, P.-G.; Ivan, O.; Adriana, B.; Diana, O.; Carolina, E. url  doi
openurl 
  Title (up) Constant light during lactation programs circadian and metabolic systems Type Journal Article
  Year 2018 Publication Chronobiology International Abbreviated Journal Chronobiol Int  
  Volume 35 Issue 8 Pages 1153-1167  
  Keywords Animals  
  Abstract Exposure to light at night is a disruptive condition for the adult circadian system, leading to arrhythmicity in nocturnal rodents. Circadian disruption is a risk factor for developing physiological and behavioral alterations, including weight gain and metabolic disease. During early stages of development, the circadian system undergoes a critical period of adjustment, and it is especially vulnerable to altered lighting conditions that may program its function, leading to long-term effects. We hypothesized that during lactation a disrupted light-dark cycle due to light at night may disrupt the circadian system and in the long term induce metabolic disorders. Here we explored in pups, short- and long-term effects of constant light (LL) during lactation. In the short term, LL caused a loss of rhythmicity and a reduction in the immunopositive cells of VIP, AVP, and PER1 in the suprachiasmatic nucleus (SCN). In the short term, the affection on the circadian clock in the pups resulted in body weight gain, loss of daily rhythms in general activity, plasma glucose and triglycerides (TG). Importantly, the DD conditions during development also induced altered daily rhythms in general activity and in the SCN. Exposure to LD conditions after lactation did not restore rhythmicity in the SCN, and the number of immunopositve cells to VIP, AVP, and PER1 remained reduced. In the long term, daily rhythmicity in general activity was restored; however, daily rhythms in glucose and TG remained disrupted, and daily mean levels of TG were significantly increased. Present results point out the programming role played by the LD cycle during early development in the function of the circadian system and on metabolism. This study points out the risk represented by exposure to an altered light-dark cycle during early stages of development. ABBREVIATIONS: AVP: arginine vasopressin peptide; CRY: cryptochrome; DD: constant darkness; DM: dorsomedial; LD: light-dark cycle; LL: constant light; NICUs: neonatal intensive care units; P: postnatal days; PER: period; S.E.M.: standard error of the mean; SCN: suprachiasmatic nucleus; TG: triglycerides; VIP: vasointestinal peptide; VL: ventrolateral; ZT: zeitgeber time.  
  Address a Facultad de Medicina , Universidad Nacional Autonoma de Mexico, UNAM , Mexico City , Mexico  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0742-0528 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:29688088 Approved no  
  Call Number GFZ @ kyba @ Serial 1884  
Permanent link to this record
 

 
Author Chen, Y.; Cheng, M.; Su, T.; Gao, T.; Yu, W. url  doi
openurl 
  Title (up) Constant light exposure aggravates POMC-mediated muscle wasting associated with hypothalamic alteration of circadian clock and SIRT1 in endotoxemia rats Type Journal Article
  Year 2018 Publication Biochemical and Biophysical Research Communications Abbreviated Journal Biochem Biophys Res Commun  
  Volume in press Issue Pages  
  Keywords Animals  
  Abstract Constant light exposure is widespread in the intensive care unit (ICU) and could increase the rate of brain dysfunction as delirium and sleep disorders in critical patients. And the activation of hypothalamic neuropeptides is proved to play a crucial role in regulating hypercatabolism, especially skeletal muscle wasting in critical patients, which could lead to serious complications and poor prognosis. Here we investigated the hypothesis that constant light exposure could aggravate skeletal muscle wasting in endotoxemia rats and whether it was associated with alterations of circadian clock and hypothalamic proopiomelanocortin(POMC) expression. Fifty-four adult male Sprague-Dawley rats were intraperitoneally injected with lipopolysaccharide(LPS) or saline, subjected to constant light or a 12:12h light-dark cycle for 7 days. On day 8, rats were sacrificed across six time points in 24h and hypothalamus tissues and skeletal muscle were obtained. Rates of muscle wasting were measured by 3-methylhistidine(3-MH) and tyrosine release as well as expression of two muscle atrophic genes, muscle ring finger 1(MuRF-1) and muscle atrophy F-box(MAFbx). The expression of circadian clock genes, silent information regulator 1(SIRT1), POMC and hypothalamic inflammatory cytokines were also detected. Results showed that LPS administration significantly increased hypothalamic POMC expression, inflammatory cytokine levels and muscle wasting rates. Meanwhile constant light exposure disrupted the circadian rhythm, declined the expression of SIRT1 as well as aggravated hypothalamic POMC overexpression and skeletal muscle wasting in rats with endotoxemia. Taken together, the results demonstrated that constant light exposure could aggravate POMC-mediated skeletal muscle wasting in endotoxemia rats, which is associated with alteration of circadian clocks and SIRT1 in the hypothalamus.  
  Address Department of Intensive Care Unit, The Affiliated Drum Tower Hospital, Medical School of Nanjing University, Nanjing, 210008, China. Electronic address: yudrnj2@163.com  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0006-291X ISBN Medium  
  Area Expedition Conference  
  Notes PMID:30528733 Approved no  
  Call Number GFZ @ kyba @ Serial 2134  
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