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Author Depner, C.M.; Melanson, E.L.; McHill, A.W.; Wright, K.P.J.
Title Mistimed food intake and sleep alters 24-hour time-of-day patterns of the human plasma proteome Type Journal Article
Year 2018 Publication Proceedings of the National Academy of Sciences of the United States of America Abbreviated Journal Proc Natl Acad Sci U S A
Volume (down) 115 Issue 23 Pages E5390-E5399
Keywords Human Health
Abstract Proteomics holds great promise for understanding human physiology, developing health biomarkers, and precision medicine. However, how much the plasma proteome varies with time of day and is regulated by the master circadian suprachiasmatic nucleus brain clock, assessed here by the melatonin rhythm, is largely unknown. Here, we assessed 24-h time-of-day patterns of human plasma proteins in six healthy men during daytime food intake and nighttime sleep in phase with the endogenous circadian clock (i.e., circadian alignment) versus daytime sleep and nighttime food intake out of phase with the endogenous circadian clock (i.e., circadian misalignment induced by simulated nightshift work). We identified 24-h time-of-day patterns in 573 of 1,129 proteins analyzed, with 30 proteins showing strong regulation by the circadian cycle. Relative to circadian alignment, the average abundance and/or 24-h time-of-day patterns of 127 proteins were altered during circadian misalignment. Altered proteins were associated with biological pathways involved in immune function, metabolism, and cancer. Of the 30 circadian-regulated proteins, the majority peaked between 1400 hours and 2100 hours, and these 30 proteins were associated with basic pathways involved in extracellular matrix organization, tyrosine kinase signaling, and signaling by receptor tyrosine-protein kinase erbB-2. Furthermore, circadian misalignment altered multiple proteins known to regulate glucose homeostasis and/or energy metabolism, with implications for altered metabolic physiology. Our findings demonstrate the circadian clock, the behavioral wake-sleep/food intake-fasting cycle, and interactions between these processes regulate 24-h time-of-day patterns of human plasma proteins and help identify mechanisms of circadian misalignment that may contribute to metabolic dysregulation.
Address Division of Endocrinology, Metabolism, and Diabetes, University of Colorado Anschutz Medical Campus, Aurora, CO 80045
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0027-8424 ISBN Medium
Area Expedition Conference
Notes PMID:29784788 Approved no
Call Number GFZ @ kyba @ Serial 1916
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Author Gaydecki, P.
Title Automated moth flight analysis in the vicinity of artificial light Type Journal Article
Year 2018 Publication Bulletin of Entomological Research Abbreviated Journal Bull Entomol Res
Volume (down) 109 Issue 1 Pages 127-140
Keywords Instrumentation; Animals
Abstract Instrumentation and software for the automated analysis of insect flight trajectories is described, intended for quantifying the behavioural dynamics of moths in the vicinity of artificial light. For its time, this moth imaging system was relatively advanced and revealed hitherto undocumented insights into moth flight behaviour. The illumination source comprised a 125 W mercury vapour light, operating in the visible and near ultraviolet wavelengths, mounted on top of a mobile telescopic mast at heights of 5 and 7.1 m, depending upon the experiment. Moths were imaged in early September, at night and in field conditions, using a ground level video camera with associated optics including a heated steering mirror, wide angle lens and an electronic image intensifier. Moth flight coordinates were recorded at a rate of 50 images per second (fields) and transferred to a computer using a light pen (the only non-automated operation in the processing sequence). Software extracted ground speed vectors and, by instantaneous subtraction of wind speed data supplied by fast-response anemometers, the airspeed vectors. Accumulated density profiles of the track data revealed that moths spend most of their time at a radius of between 40 and 50 cm from the source, and rarely fly directly above it, from close range. Furthermore, the proportion of insects caught by the trap as a proportion of the number influenced by the light (and within the field of view of the camera) was very low; of 1600 individual tracks recorded over five nights, a total of only 12 were caught. Although trap efficiency is strongly dependent on trap height, time of night, season, moonlight and weather, the data analysis confirmed that moths do not exhibit straightforward positive phototaxis. In general, trajectory patterns become more complex with reduced distance from the illumination, with higher recorded values of speeds and angular velocities. However, these characteristics are further qualified by the direction of travel of the insect; the highest accelerations tended to occur when the insect was at close range, but moving away from the source. Rather than manifesting a simple positive phototaxis, the trajectories were suggestive of disorientation. Based on the data and the complex behavioural response, mathematical models were developed that described ideal density distribution in calm air and light wind speed conditions. The models did not offer a physiological hypothesis regarding the behavioural changes, but rather were tools for quantification and prediction. Since the time that the system was developed, instrumentation, computers and software have advanced considerably, allowing much more to be achieved at a small fraction of the original cost. Nevertheless, the analytical tools remain useful for automated trajectory analysis of airborne insects.
Address School of Electrical and Electronic Engineering, University of Manchester,Manchester M13 9PL,UK
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0007-4853 ISBN Medium
Area Expedition Conference
Notes PMID:29745349 Approved no
Call Number GFZ @ kyba @ Serial 1895
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Author Kumar, P.; Sajjad, H.; Joshi, P.K.; Elvidge, C.D.; Rehman, S.; Chaudhary, B.S.; Tripathy, B.R.; Singh, J.; Pipal, G.
Title Modeling the luminous intensity of Beijing, China using DMSP-OLS night-time lights series data for estimating population density Type Journal Article
Year 2018 Publication Physics and Chemistry of the Earth, Parts A/B/C Abbreviated Journal Physics and Chemistry of the Earth, Parts A/B/C
Volume (down) 109 Issue Pages 31-39
Keywords Remote Sensing
Abstract Various scientific researches were conducted to monitor human activities and natural phenomena with the availability of various night time satellite data such as Defense Meteorological Satellite Program (DMPS). Population growth especially in a faster growing economy like China is an important indicator for assessing socio-economic development, urban planning and environmental management. Thus, spatial distribution of population is instrumental in assessing growth and developmental activities in Beijing city of China. The satellite observation data derived from Defense Meteorological Satellite Program (DMSP) was utilized to estimate population density through the measurement of light flux with radiometric recording. The data was calibrated using C0, C1, C2 parameters before processing. Population density of Beijing city was estimated using light volume of this calibrated data. Regression analysis between urban population and light volume revealed high correlation (r2=0.89)r2=0.89). Thus, population density can effectively be estimated using light intensity. The model used for estimating urban population density can effectively be utilized for other major cities of the world.
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1474-7065 ISBN Medium
Area Expedition Conference
Notes Approved no
Call Number GFZ @ kyba @ Serial 1934
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Author Gwiazdsinski, L.; Straw, W.
Title Nights and Mountains. Preliminary Explorations of a Double Frontier Type Journal Article
Year 2018 Publication Revue de géographie alpine Abbreviated Journal rga
Volume (down) 106 Issue 1 Pages
Keywords Commentary; Darkness
Abstract
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0035-1121 ISBN Medium
Area Expedition Conference
Notes Approved no
Call Number GFZ @ kyba @ Serial 1866
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Author Challéat, S.; Lapostolle, D.; Milian, J.
Title The Night-time Environment in French Mountain Areas. A Resource and a Transition Operator Towards Sustainability Type Journal Article
Year 2018 Publication Revue de géographie alpine Abbreviated Journal rga
Volume (down) 106 Issue 1 Pages
Keywords Darkness; Society
Abstract This article presents our approach to construct the night-time environment (NE) as an interdisciplinary research subject. Understood within the framework of various French mountain areas, we show that the NE is highly indicative of different development trajectories. We analyse them by combining traditional social science research into territory with the ecosystem approaches of the experimental sciences. We show how the NE resource (NER) is transformed into an operator that facilitates the transition towards sustainability. By highlighting three of the NE’s specifications, this work lays the groundwork for a transdisciplinary approach.
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0035-1121 ISBN Medium
Area Expedition Conference
Notes Approved no
Call Number GFZ @ kyba @ Serial 1867
Permanent link to this record